Uses: used both as a food preservative, but also manufacture of new antihypertensive drugs angiotensin converting enzyme inhibitors (ACE-I) - Enalapril (Enalapril) and ramipril (Ramipril) common intermediate body. Plymouth Intermediates
Ethyl 3-benzoylacrylate and its ethyl ester (17450-56-5) can be used as a food preservative, a perfume, an important intermediate of pharmaceutical and pesticide; especially when angiotensin converting enzyme inhibitors (ACE-I) P Lee drugs in clinical practice is recommended as first-line treatment of hypertension drugs, the market demand gradually increased. Because 3-benzoyl acrylic acid and its ethyl ester is Enalapril (Enalapril) and ramipril (Ramipril) common intermediates [1.2j. Document "1 benzene as starting material, the use of maleic anhydride, benzene, anhydrous aluminum chloride as a catalyst for the reaction Fu one grams, after hydrolysis, washing and drying to obtain 3-benzoyl acid. The esterification is using sulfuric acid as a catalyst, 3-benzoyl acrylic acid with anhydrous ethanol synthetic route.
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